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5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H
Nutlin-3 does not induce the phosphorylation of p53 on key serine residues and reveals no difference in their sequence-specific DNA binding and ability to transactivate p53 target genes compared with phosphorylated p53 induced by the genotoxic drugs doxorubicin and etoposide
ML-277 shows 1000-fold greater selectivity for the Chk2 serine/threonine kinase than for the Cdk1/B and CK1 kinases (for which IC50 = 12 μM and 17 μM
InChi: InChI=1S/C16H12O5/c1-20-14-5-2-9(6-13(14)18)12-8-21-15-7-10(17)3-4-11(15)16(12)19/h2-8
CAS Number: 705946-27-6
Diflunisal 15654 5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3HDiflunisal (MK 647) is a salicylate derivative with nonsteroidal anti inflammatory and uricosuric properties, which is used alone as an analgesic and in rheumatoid arthritis patients. The mechanism of action of diflunisal is as a Cyclooxygenase (COX) Inhibitor. Product information CAS Number: 22494 42 4 Molecular Weight: 250. 20 Formula: C13H8F2O3 Chemical Name: 2',4' difluoro 4 hydroxy [1,1' biphenyl] 3 carboxylic acid Smiles:
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